Author: Korner, Kathryn

Lubonja’s research published in ‘Science of Advanced Materials’

Before Klair Lubonja even started classes his freshman year he was engaged in research courtesy of the Pre-College Enrichment Program, sponsored by the Department of Health Career Opportunity Programs at the UConn Health Center. As a member of Dr. Yu Lei’s lab, Klair spent the summer working with copper nanowire and single-wired carbon nanotubes in an effort to enhance glucose electrooxidation. Continue reading →

Rowe Researcher: Translesional Synthesis DNA Polymerases

Summer 2012: Structure and Interactions of Translesional Synthesis DNA Polymerases

By Maciej Kosakowski, Dr. Dmitry Korzhnev, Ph.D., Dr. Irena Bezsonova, Ph.D.

During my weeks with the College Summer Fellowship Program at the UConn Health Center, I worked in a structural biology lab in conjunction with the NMR lab under Dr. Korzhnev. I assisted him on his project, which aimed to discover the specific mechanisms behind translesional synthesis DNA polymerases, or TLS polymerases for short. Continue reading →

Rowe Researcher: Health in the Buduburam Refugee Camp

Summer 2012: The Socio-Political Influences on Health in the Buduburam Refugee Camp

By Gian Grant, Dr. Elizabeth Holzer

The United Nations High Commissioner of Refugees (UNHCR) recognizes that there are approximately 2.7 million refugees in the world. The UNHCR often coordinates with non-governmental organizations and asylum countries to provide refugees with services such as health care until a permanent residential situation is agreed upon. Continue reading →

Rowe Researcher: Characterization of Drosophila Interacting Genes

Daniel Camacho conducting research at the Health Center.
Daniel Camacho conducting research at the Health Center.

Summer 2012: Characterization of Drosophila Interacting Genes: Elucidating the Mechanism(s) of PolyQ Toxicity in Huntington’s Disease

By Daniel R. Camacho, Ping Zhang, Ph.D.

Polyglutamine expansions are a type of genetic mutation that is responsible for several human neurodegenerative diseases, including Huntington’s disease. The pathology of these diseases involves the accumulation of proteins containing polyglutamine domains within neuronal cells, which ultimately leads to cell death. The mechanism of toxicity of these protein aggregates is currently being investigated. My work involved using the model genetic organism Drosophila melanogaster to try to elucidate aspects of polyglutamine toxicity. Continue reading →

Rowe Researcher: Social Interaction and Anxiety in Mice

Ashley Bonet with her research poster.
Ashley Bonet with her research poster.

Spring 2012: Social Interaction and Anxiety in Mutant BXD29 Mice

By A.C.Bonet1 , D.T.Truong2 , R.H. Fitch, PhD1

            The purpose of this research was to observe anxiety and social interaction in the BXD29 mice strain. BXD29/Ty -wild type and BXD29-Tlr4lps-2J/J -mutant mice have never been tested for social interaction or anxiety related behaviors, thus this research offers a preliminary observation of the behaviors. The BXD29-Tlr4lps-2J/J mice have subcortical heterotopias formed by neurons destined for layers 2-4 of the neocortex as well as partial callosal agenesis. Continue reading →

Rowe Researcher: Transition from NICU to Home

Stephanie Jorge in the NICU.

Summer 2011: Family Empowerment in the Transition from NICU to Home: Evaluating the March of Dimes Family Support Program

By Stephanie R Jorge, Regina M. Cusson, Ph.D., NNP-BC, APRN, FAAN

The University of Connecticut Health Center’s (UCHC) March of Dimes Neonatal Intensive Care Unit (NICU) Family Support Program (MODFSP) provides families of NICU patients with programs, support specialists, educational materials, and community resources to aide in the emotional and physical adaptation to a new life with a premature infant. Continue reading →